ASB11 antibody (C-Term)

Catalog No. ABIN2784642

Product Details anti-ASB11 Antibody

Target: ASB11 (Ankyrin Repeat and SOCS Box-Containing 11 (ASB11))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB11 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GQWLDTPLHA AARQSNVEVI HLLTDYGANL KRRNAQGKSA LDLAAPKSSV

Predicted Reactivity: Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ASB11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ASB11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 302 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB11

Target: ASB11 (Ankyrin Repeat and SOCS Box-Containing 11 (ASB11))

Alternative Name: ASB11 (ASB11 Products)

Background: ASB11 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation.The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp779E2460, MGC119168, MGC119169
Protein Interaction Partner: GANAB, ERLIN1, CUL5, UBC, SLC3A2, RPN1, PSMD11, PSMD2, PSMC3, PSMB2, PSMA2, PRPS1, DDOST, ATP5B,
Protein Size: 302

Molecular Weight: 33 kDa

Gene ID: 140456

NCBI Accession: NM_001012428, NP_001012428

UniProt: Q8WXH4