SFRS12 antibody (N-Term)

Catalog No. ABIN2784667

Product Details anti-SFRS12 Antibody

Target: SFRS12 (SREK1) (Splicing Regulatory Glutamine/lysine-Rich Protein 1 (SREK1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DPSSVGVAQH LTNTVFIDRA LIVVPCAEGK IPEESKALSL LAPAPTMTSL

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SFRS12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SFRS12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 624 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SFRS12 antibody (ABIN2784667)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for SFRS12

Target: SFRS12 (SREK1) (Splicing Regulatory Glutamine/lysine-Rich Protein 1 (SREK1))

Alternative Name: SFRS12 (SREK1 Products)

Synonyms: SFRS12 antibody, SRrp508 antibody, SRrp86 antibody, Sfrs12 antibody, Srrp86 antibody, Srsf12 antibody, 8430401B01 antibody, AI450757 antibody, AI462342 antibody, zgc:100974 antibody, splicing regulatory glutamic acid and lysine rich protein 1 antibody, splicing regulatory glutamine/lysine-rich protein 1 antibody, SREK1 antibody, Srek1 antibody, srek1 antibody

Background: SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins.SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002 [PubMed 11991645]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-78 AW963850.1 1-78 79-415 AK091758.1 1-337 416-2238 BC067770.1 609-2431 2239-3654 BC112343.1 1800-3215 3655-3660 AK125893.1 3379-3384 3661-4030 AL049309.1 705-1074
Alias Symbols: DKFZp564B176, MGC133045, SRrp508, SRrp86, SFRS12
Protein Interaction Partner: SREK1, SRSF11, LIN28A, SRPK2, SRPK1, MDM2, VPS33A, CUL1, ELAVL1, HNRNPA1, DDX3X, CSNK2B, C1QBP, PARP1, HNRNPCL1, HNRNPA3, NFATC2IP, SH3GLB2, RBMX, PABPC1, SRPK3, SF3B3, SUPT16H, SF3A3, SRSF8, SRSF10, DDX17, GNB2L1, THRAP3, ZRANB2, EFTUD2, PABPC4, SRSF9, D
Protein Size: 624

Molecular Weight: 72 kDa

Gene ID: 140890

NCBI Accession: NM_001077199, NP_001070667