DPYSL2 antibody (Middle Region)

Catalog No. ABIN2784711

Product Details anti-DPYSL2 Antibody

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPYSL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Sequence: NIFEGMECRG SPLVVISQGK IVLEDGTLHV TEGSGRYIPR KPFPDFVYKR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against DPYSL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DPYSL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 572 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DPYSL2

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Alternative Name: DPYSL2 (DPYSL2 Products)

Synonyms: CRMP-2 antibody, CRMP2 antibody, DHPRP2 antibody, DRP-2 antibody, DRP2 antibody, N2A3 antibody, ULIP-2 antibody, ULIP2 antibody, TOAD-64 antibody, crmp2 antibody, dhprp2 antibody, drp-2 antibody, drp2 antibody, unc-33 antibody, unc33 antibody, dpysl2 antibody, CRMP 2 antibody, PCRMP 2 antibody, PCRMP-2 antibody, PCRMP2 antibody, PfCRMP 2 antibody, PfCRMP-2 antibody, AI851130 antibody, Crmp2 antibody, Musunc33 antibody, Ulip2 antibody, CRMP2A antibody, dihydropyrimidinase like 2 antibody, dihydropyrimidinase-like 2 antibody, dihydropyrimidinase like 2 L homeolog antibody, dihydropyrimidinase-like 2b antibody, cysteine repeat modular protein 2, putative antibody, DPYSL2 antibody, dpysl2.L antibody, dpysl2b antibody, PfCRMP2 antibody, dpysl2 antibody, Dpysl2 antibody

Background: DPYSL2 belongs to the DHOase family. It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. The protein plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Alias Symbols: CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP2, CRMP-2, ULIP-2
Protein Interaction Partner: DPYSL5, GORASP2, UBC, DPYSL3, DPYSL2, CRMP1, PUS7, RANBP6, XPO7, HSPH1, EIF3J, PDE3A, DNAJB1, LEF1, IQCB1, TUBB, TUBA1A, Htt, CDK2, SIRT7, ELAVL1, DISC1, TNIK, DPYSL4, GSK3B, NUMB, PLD2, ROCK1, RHOA, AP2A1,
Protein Size: 572

Molecular Weight: 62 kDa

Gene ID: 1808

NCBI Accession: NM_001386, NP_001377

UniProt: Q16555

Pathways: Regulation of Cell Size