CRYM antibody (N-Term)

Catalog No. ABIN2784721

Product Details anti-CRYM Antibody

Target: CRYM (Crystallin, mu (CRYM))

Binding Specificity: N-Term

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYM antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ALTTKLVTFY EDRGITSVVP SHQATVLLFE PSNGTLLAVM DGNVITAKRT

Predicted Reactivity: Cow: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CRYM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CRYM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRYM

Target: CRYM (Crystallin, mu (CRYM))

Alternative Name: CRYM (CRYM Products)

Synonyms: CRYM antibody, zgc:158843 antibody, DFNA40 antibody, THBP antibody, crystallin mu antibody, crystallin, mu antibody, Cro/Cl family transcriptional regulator antibody, crystallin mu L homeolog antibody, CRYM antibody, crym antibody, EAMY_RS27495 antibody, crym.L antibody, Crym antibody

Background: Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: DFNA40, THBP
Protein Interaction Partner: TERF1, C7orf25, CDC37,
Protein Size: 314

Molecular Weight: 34 kDa

Gene ID: 1428

NCBI Accession: NM_001888, NP_001879

UniProt: Q14894

Pathways: Hormone Transport, Sensory Perception of Sound