PDIA6 antibody (Middle Region)

Catalog No. ABIN2784776

Product Details anti-PDIA6 Antibody

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDIA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KLAAVDATVN QVLASRYGIR GFPTIKIFQK GESPVDYDGG RTRSDIVSRA

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PDIA6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDIA6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 440 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDIA6

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Alternative Name: PDIA6 (PDIA6 Products)

Synonyms: 1700015E05Rik antibody, AL023058 antibody, C77895 antibody, CaBP5 antibody, P5 antibody, Txndc7 antibody, ERP5 antibody, TXNDC7 antibody, CaBP1 antibody, pdi-p5 antibody, erp5 antibody, pdia6 antibody, pdip5 antibody, txndc7 antibody, protein disulfide isomerase family A member 6 antibody, protein disulfide isomerase associated 6 antibody, protein disulfide isomerase family A, member 6 antibody, protein disulfide isomerase family A member 6 L homeolog antibody, PDIA6 antibody, Pdia6 antibody, pdia6.L antibody

Background: Protein disulfide isomerases, such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins.Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995 [PubMed 7590364]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-39 BF979486.1 11-49 40-1858 BC001312.1 1-1819 1859-2326 AK127433.1 2215-2682 2327-2344 BM511594.1 1-18 c
Alias Symbols: ERP5, P5, TXNDC7
Protein Interaction Partner: HUWE1, UBC, MDM2, P3H1, XPO5, MAT2B, NRD1, GTF2A1, C1QBP, ARPC4, UGDH, TPD52L2, TPD52, PPP3CA, PFDN5, PCYT1A, PARK2, UBD, ADRB2, IGSF8, CD81, MTNR1A, FN1, CSNK2A1, CASP8, METTL23, GRDX, gag-pol, CLN8, VKORC1, SMURF1, TXNL1, MACF1, TPI1, PMS2P1, P4HB, IGBP
Protein Size: 440

Molecular Weight: 48 kDa

Gene ID: 10130

NCBI Accession: NM_005742, NP_005733

UniProt: Q15084

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis