NUP50 antibody (C-Term)

Catalog No. ABIN2784862

Product Details anti-NUP50 Antibody

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP50 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: TTQSKPVSSP FPTKPLEGQA EGDSGECKGG DEEENDEPPK VVVTEVKEED

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 91%, Pig: 100%, Rabbit: 100%, Rat: 92%, Yeast: 80%

Characteristics: This is a rabbit polyclonal antibody against NUP50. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NUP50

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 468 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NUP50

Target: NUP50 (Nucleoporin 50kDa (NUP50))

Alternative Name: NUP50 (NUP50 Products)

Synonyms: wu:fa56e03 antibody, wu:fb78a08 antibody, GB18194 antibody, npap60 antibody, npap60l antibody, Nup50 antibody, Rtp60 antibody, 1700030K07Rik antibody, AI413123 antibody, Npap60 antibody, NPAP60 antibody, NPAP60L antibody, nucleoporin 50 antibody, nuclear pore complex protein Nup50 antibody, nucleoporin 50kDa S homeolog antibody, nucleoporin 50kDa antibody, nup50 antibody, LOC410864 antibody, NUP50 antibody, nup50.S antibody, CpipJ_CPIJ012737 antibody, Nup50 antibody

Background: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import.The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC39961, NPAP60, NPAP60L
Protein Interaction Partner: KPNA5, KPNA4, KPNA3, KPNA2, KPNA1, KPNA6, UBC, KIAA1033, SART3, TTI1, TSC22D1, IKBKAP, KIF5B, EPB41L1, ACACA, SRPK2, LMNA, HDAC6, NPM1, UBAP2, TOR1AIP1, NUP153, APP, CUL3, Mki67, Kifc5b, SLX4, KPNB1, XPO1, RAN, CDKN1B, IPO13,
Protein Size: 468

Molecular Weight: 50 kDa

Gene ID: 10762

NCBI Accession: NM_007172, NP_009103

UniProt: Q9UKX7

Pathways: Tube Formation