WIF1 antibody (N-Term)

Catalog No. ABIN2784868

Product Details anti-WIF1 Antibody

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIF1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RKAQQRMPAI PVNIHSMNFT WQAAGQAEYF YEFLSLRSLD KGIMADPTVN

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against WIF1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WIF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 379 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WIF1

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Alternative Name: WIF1 (WIF1 Products)

Synonyms: shf antibody, GB10372 antibody, wif-1 antibody, WIF1 antibody, WIF-1 antibody, AW107799 antibody, zgc:110507 antibody, protein shifted antibody, wnt inhibitory factor 1 antibody, WNT inhibitory factor 1 antibody, Wnt inhibitory factor 1 antibody, WNT inhibitory factor 1 S homeolog antibody, LOC552805 antibody, CpipJ_CPIJ003761 antibody, wif1 antibody, WIF1 antibody, Wif1 antibody, LOC100511326 antibody, wif1.S antibody

Background: The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.
Alias Symbols: WIF-1
Protein Interaction Partner: KRTAP10-3, KRTAP10-8, ICOS, RPL37, WNT1,
Protein Size: 379

Molecular Weight: 38 kDa

Gene ID: 11197

NCBI Accession: NM_007191, NP_009122

UniProt: Q9Y5W5

Pathways: WNT Signaling, Positive Regulation of fat Cell Differentiation