GABARAPL2 antibody (N-Term)

Catalog No. ABIN2784885

Product Details anti-GABARAPL2 Antibody

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Rabbit, Dog, Guinea Pig, Horse, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAPL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KWMFKEDHSL EHRCVESAKI RAKYPDRVPV IVEKVSGSQI VDIDKRKYLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against GABARAPL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABARAPL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 117 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABARAPL2

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Alternative Name: GABARAPL2 (GABARAPL2 Products)

Synonyms: GABARAPL2 antibody, atg8 antibody, gef2 antibody, gate16 antibody, gate-16 antibody, Gef2 antibody, ATG8 antibody, ATG8C antibody, GATE-16 antibody, GATE16 antibody, GEF-2 antibody, GEF2 antibody, zgc:92319 antibody, 0610012F20Rik antibody, 2900019O08Rik antibody, AI173605 antibody, GABA type A receptor associated protein like 2 antibody, GABA(A) receptor-associated protein like 2 antibody, GABA(A) receptor-associated protein like 2 L homeolog antibody, gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2 antibody, GABARAPL2 antibody, gabarapl2 antibody, Gabarapl2 antibody, gabarapl2.L antibody

Background: GABARAPL2 belongs to the MAP1 LC3 family. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. The protein first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
Alias Symbols: ATG8, GATE-16, GATE16, GEF-2, GEF2, ATG8C
Protein Interaction Partner: GIMAP6, KRTAP10-9, KRTAP10-7, KIAA1958, CCDC155, FUNDC1, AHNAK2, TSR2, UBA5, CALCOCO1, AGTRAP, ARFGAP1, BCL2L13, SIK2, TBC1D9B, TNIP1, CALCOCO2, TBC1D5, SQSTM1, UBC, MLX, MAP1LC3B, WWOX, ATG4A, BNIP3L, SGTA, VAPA, CLN8, APP, ATG13, ULK2, ULK1, NBR1, TBC1D
Protein Size: 117

Molecular Weight: 14 kDa

Gene ID: 11345

NCBI Accession: NM_007285, NP_009216

UniProt: P60520

Pathways: Autophagy