ALDH1L1 antibody (Middle Region)

Catalog No. ABIN2784888

Product Details anti-ALDH1L1 Antibody

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1L1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LTLKAGIPKG VVNVLPGSGS LVGQRLSDHP DVRKIGFTGS TEVGKHIMKS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Sheep: 100%, Yeast: 79%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ALDH1L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ALDH1L1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 902 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDH1L1

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Alternative Name: ALDH1L1 (ALDH1L1 Products)

Synonyms: 10-FTHFDH antibody, 10-fTHF antibody, FDH antibody, FTHFD antibody, Fthfd antibody, 1810048F20Rik antibody, Neut2 antibody, fthfd antibody, ALDH1L1 antibody, DKFZp469C068 antibody, aldehyde dehydrogenase 1 family member L1 antibody, aldehyde dehydrogenase 1 family, member L1 antibody, cytosolic 10-formyltetrahydrofolate dehydrogenase antibody, aldehyde dehydrogenase 1 family member L1 L homeolog antibody, ALDH1L1 antibody, Aldh1l1 antibody, aldh1l1 antibody, LOC476506 antibody, LOC100465263 antibody, aldh1l1.L antibody

Background: ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
Alias Symbols: DKFZp781N0997, FTHFD, FDH, 10-fTHF
Protein Size: 902

Molecular Weight: 99 kDa

Gene ID: 10840

NCBI Accession: NM_012190, NP_036322

UniProt: O75891