FBXO32 antibody (C-Term)

Catalog No. ABIN2785131

Product Details anti-FBXO32 Antibody

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO32 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LVRCYPRREQ YGVTLQLCKH CHILSWKGTD HPCTANNPES CSVSLSPQDF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 92%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against Fbxo32. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region from the human protein.

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 355 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO32

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Alternative Name: Fbxo32 (FBXO32 Products)

Synonyms: MGC56479 antibody, zgc:56479 antibody, Fbx32 antibody, MAFbx antibody, 4833442G10Rik antibody, AI430017 antibody, ATROGIN1 antibody, Gm20361 antibody, Atrogin1 antibody, F-box protein 32 antibody, fbxo32 antibody, FBXO32 antibody, Fbxo32 antibody

Background: Fbxo32 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy.
Alias Symbols: 4833442G10Rik, AI430017, ATROGIN1, MAFbx, atrogin-1, Gm20361
Protein Interaction Partner: Nfkbia, Myod1, Telo2, 9130011E15Rik, Prdm16, Ube2v2, Taf15, Inf2, Sync, Rps13, Tubb6, Fbxo32, Rplp2, Eef1g, Rpl14, Cand2, Srp72, Ube2v1, Ahnak, Eif3f, Atp5d, Srsf4, Adrm1, Mettl3, Pgam2, Eef1b2, Ubqln2, Ywhab, Clpp, Hnrnpa2b1, Mybph, Thop1, Eif3b, Cul1, C
Protein Size: 355

Molecular Weight: 39 kDa

Gene ID: 67731

NCBI Accession: NM_026346, NP_080622

UniProt: Q9CPU7