GGN antibody (N-Term)

Catalog No. ABIN2785224

Product Details anti-GGN Antibody

Target: GGN (Gametogenetin (GGN))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GPSKWQKPAG TPVPRIRRLL EASHRGQGDP PSLRPLKPPP PPRQLSVKDT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GGN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GGN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 652 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GGN

Target: GGN (Gametogenetin (GGN))

Alternative Name: GGN (GGN Products)

Synonyms: AI593290 antibody, gametogenetin antibody, GGN antibody, Ggn antibody

Background: GGN may be involved in spermatogenesis.This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis.
Alias Symbols: FLJ35713, MGC33369
Protein Interaction Partner: KRT40, ECT2, BRCA1, OAZ3, GGNBP2, GGN, FANCL,
Protein Size: 652

Molecular Weight: 67 kDa

Gene ID: 199720

NCBI Accession: NM_152657, NP_689870

UniProt: Q86UU5