ENPP6 antibody (Middle Region)

Catalog No. ABIN2785260

Product Details anti-ENPP6 Antibody

Target: ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Pig, Rabbit, Cow, Zebrafish (Danio rerio), Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ELMDMRGIFL AFGPDFKSNF RAAPIRSVDV YNVMCNVVGI TPLPNNGSWS

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ENPP6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ENPP6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 440 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ENPP6

Target: ENPP6 (Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6))

Alternative Name: ENPP6 (ENPP6 Products)

Synonyms: E-NPP 6 antibody, cb1028 antibody, sb:cb727 antibody, zgc:103605 antibody, NPP6 antibody, NPP-6 antibody, 4833421B01Rik antibody, B830047L21Rik antibody, D8Ertd514e antibody, Npp6 antibody, E-NPP6 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 6 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 6 L homeolog antibody, enpp6 antibody, enpp6.L antibody, ENPP6 antibody, Enpp6 antibody

Background: ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase. ENPP6 hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. ENPP6 hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.
Alias Symbols: MGC33971, NPP6
Protein Size: 440

Molecular Weight: 50 kDa

Gene ID: 133121

NCBI Accession: NM_153343, NP_699174

UniProt: Q6UWR7