ASB6 antibody (Middle Region)

Catalog No. ABIN2785356

Product Details anti-ASB6 Antibody

Target: ASB6 (Ankyrin Repeat and SOCS Box Containing 6 (ASB6))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LKMAELGLTR AADVLLRHGA NLNFEDPVTY YTALHIAVLR NQPDMVELLV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ASB6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASB6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 421 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB6

Target: ASB6 (Ankyrin Repeat and SOCS Box Containing 6 (ASB6))

Alternative Name: ASB6 (ASB6 Products)

Synonyms: zgc:110231 antibody, 2510004M11Rik antibody, AA409356 antibody, ankyrin repeat and SOCS box containing 6 antibody, ankyrin repeat and SOCS box containing 6 S homeolog antibody, ankyrin repeat and SOCS box-containing 6 antibody, asb6 antibody, asb6.S antibody, ASB6 antibody, Asb6 antibody

Background: ASB6 belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases.The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases.
Alias Symbols: FLJ20548, MGC1024
Protein Interaction Partner: FAM9B, L3MBTL3, RNF41, CADPS2, HIF1AN, ASB3, RNF7, CUL5, TCEB2, HSPB1, FGG, FGB, FGA, SLC25A5, OGFOD1, MCTS1, PROSC, XPNPEP1, EZR, HDGF, FH, ATIC, HSP90AA1, APP, UBD, UBC, DCUN1D1, COPS5, CUL4B, TCEB1, ELAVL1, SH2B2,
Protein Size: 421

Molecular Weight: 46 kDa

Gene ID: 140459

NCBI Accession: NM_017873, NP_060343

UniProt: Q9NWX5