IL-24 antibody (C-Term)
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- Target See all IL-24 (IL24) Antibodies
- IL-24 (IL24) (Interleukin 24 (IL24))
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Binding Specificity
- C-Term
- Reactivity
- Human, Rat, Mouse, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL-24 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- STLANNFVLI VSQLQPSQEN EMFSIRDSAH RRFLLFRRAF KQLDVEAALT
- Predicted Reactivity
- Dog: 77%, Horse: 85%, Human: 100%, Mouse: 85%, Rat: 85%
- Characteristics
- This is a rabbit polyclonal antibody against IL24. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of IL24
- Top Product
- Discover our top product IL24 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 207 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IL-24 (IL24) (Interleukin 24 (IL24))
- Alternative Name
- IL24 (IL24 Products)
- Synonyms
- C49A antibody, FISP antibody, IL10B antibody, MDA7 antibody, MOB5 antibody, ST16 antibody, Mda7 antibody, St16 antibody, Mda-7 antibody, IL24 antibody, interleukin 24 antibody, IL24 antibody, Il24 antibody
- Background
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This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7, MOB5
Protein Interaction Partner: DCD, RARG, CCR5, CLU, UBC, IL20RA,
Protein Size: 207 - Molecular Weight
- 22 kDa
- Gene ID
- 11009
- NCBI Accession
- NM_001185156, NP_001172085
- UniProt
- Q53XZ7
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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