ASB7 antibody (Middle Region)

Catalog No. ABIN2785404

Product Details anti-ASB7 Antibody

Target: ASB7 (Ankyrin Repeat and SOCS Box Containing 7 (ASB7))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QTPLHLSALR DDVLCARMLY NYGADTNTRN YEGQTPLAVS ISISGSSRPC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ASB7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASB7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 318 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB7

Target: ASB7 (Ankyrin Repeat and SOCS Box Containing 7 (ASB7))

Alternative Name: ASB7 (ASB7 Products)

Synonyms: AI449039 antibody, Asb-7 antibody, D030055C23Rik antibody, asb7 antibody, zgc:77381 antibody, ASB-7 antibody, ankyrin repeat and SOCS box containing 7 antibody, ankyrin repeat and SOCS box-containing 7 antibody, ankyrin repeat and SOCS box containing 7 L homeolog antibody, ASB7 antibody, Asb7 antibody, asb7.L antibody, asb7 antibody

Background: The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
Alias Symbols: FLJ22551
Protein Interaction Partner: HMBOX1, CCDC136, HIF1AN, ASB4, GANAB, CCT7, RNF7, CUL5, VCL, TCEB2, TCEB1, FGG, FGB, FGA, ATF4, UBD, SRRM1,
Protein Size: 318

Molecular Weight: 36 kDa

Gene ID: 140460

NCBI Accession: NM_198243, NP_937886

UniProt: Q9H672