GRK4 antibody (Middle Region)

Catalog No. ABIN2785448

Product Details anti-GRK4 Antibody

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Horse, Zebrafish (Danio rerio), Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EKVKWEEVDQ RIKNDTEEYS EKFSEDAKSI CRMLLTKNPS KRLGCRGEGA

Predicted Reactivity: Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 92%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against GRK4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRK4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 546 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GRK4

Target: GRK4 (G Protein-Coupled Receptor Kinase 4 (GRK4))

Alternative Name: GRK4 (GRK4 Products)

Synonyms: GPRK2L antibody, GPRK4 antibody, GRK4a antibody, IT11 antibody, A830025H08Rik antibody, GRK antibody, Gprk2l antibody, Gprk4 antibody, AMPK antibody, AMPKalpha antibody, CG3051 antibody, DmAMPK alpha antibody, Dmel\\CG3051 antibody, EG:132E8.2 antibody, FBgn0023169 antibody, Gprk-4 antibody, ampk antibody, ampkalpha antibody, dAMPKa antibody, dAMPKalpha antibody, snf1a antibody, gprk4 antibody, gprk4-a antibody, grk4 antibody, GRK4 antibody, gprk4-b antibody, zgc:153020 antibody, gprk2l antibody, grk4a antibody, it11 antibody, G protein-coupled receptor kinase 4 antibody, AMP-activated protein kinase alpha subunit antibody, G protein-coupled receptor kinase 4 L homeolog antibody, G protein-coupled receptor kinase 4 S homeolog antibody, GRK4 antibody, Grk4 antibody, AMPKalpha antibody, grk4.L antibody, grk4.S antibody, grk4 antibody, LOC100540688 antibody

Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension.
Alias Symbols: GPRK2L, GPRK4, GRK4a, IT11
Protein Interaction Partner: HSP90AA1, UBC, NEDD4, IKBKG, FSHR, CALM1, BDKRB2,
Protein Size: 546

Molecular Weight: 60 kDa

Gene ID: 2868

NCBI Accession: NM_001004056, NP_001004056

UniProt: P32298

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling