IFT122 antibody (C-Term)

Catalog No. ABIN2785593

Product Details anti-IFT122 Antibody

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFT122 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QADPAQKDTM LGKFYHFQRL AELYHGYHAI HRHTEDPFSV HRPETLFNIS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against IFT122. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IFT122

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1131 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IFT122

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Alternative Name: IFT122 (IFT122 Products)

Synonyms: C86139 antibody, Wdr10 antibody, sopb antibody, CED antibody, CED1 antibody, SPG antibody, WDR10 antibody, WDR10p antibody, WDR140 antibody, intraflagellar transport 122 antibody, intraflagellar transport protein 122 homolog antibody, IFT122 antibody, ift122 antibody, LOC100639275 antibody, LOC100649523 antibody, Ift122 antibody

Background: IFT122 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. IFT122 contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: SPG, WDR10, WDR10p, WDR140, CED
Protein Interaction Partner: UBC, gag-pol,
Protein Size: 1131

Molecular Weight: 129 kDa

Gene ID: 55764

NCBI Accession: NM_052990, NP_443716

UniProt: Q9HBG6

Pathways: Tube Formation, Embryonic Body Morphogenesis