PAOX antibody (Middle Region)

Catalog No. ABIN2785615

Product Details anti-PAOX Antibody

Target: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAOX antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RGSAVGMEGG RPPPQSVGPA GAAAQAQALA GPSLLCSTRV GGRLGPSFLL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PAOX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PAOX

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 486 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAOX

Target: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Alternative Name: PAOX (PAOX Products)

Synonyms: PAO antibody, mpao1 antibody, 2410012F02Rik antibody, AI118225 antibody, Pao antibody, pao antibody, polyamine oxidase antibody, polyamine oxidase 1 antibody, amine oxidase family protein antibody, si:dkey-275b16.2 antibody, polyamine oxidase (exo-N4-amino) antibody, polyamine oxidase (exo-N4-amino) L homeolog antibody, PAOX antibody, pao1 antibody, NFIA_077590 antibody, POPTR_0011s12590g antibody, si:dkey-275b16.2 antibody, Paox antibody, paox.L antibody

Background: PAOX belongs to the flavin monoamine oxidase family. PAOX is a flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. It can also oxidize N(1)-acetylspermidine to putrescine. PAOX does not oxidize spermidine. It plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Alias Symbols: DKFZp434J245, MGC45464, PAO, RP11-122K13.11
Protein Interaction Partner: PEX5,
Protein Size: 486

Molecular Weight: 53 kDa

Gene ID: 196743

NCBI Accession: NM_207128, NP_997011