ERCC5 antibody (N-Term)

Catalog No. ABIN2785634

Product Details anti-ERCC5 Antibody

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NPQAIDIESE DFSSLPPEVK HEILTDMKEF TKRRRTLFEA MPEESDDFSQ

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ERCC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1186 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERCC5

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Alternative Name: ERCC5 (ERCC5 Products)

Synonyms: COFS3 antibody, ERCM2 antibody, UVDR antibody, XPG antibody, XPGC antibody, cofs3 antibody, ercm2 antibody, uvdr antibody, xpg antibody, xpgc antibody, Xpg antibody, ERCC excision repair 5, endonuclease antibody, excision repair cross-complementation group 5 L homeolog antibody, excision repair cross-complementing rodent repair deficiency, complementation group 5 antibody, ERCC5 antibody, ercc5.L antibody, Ercc5 antibody

Background: Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: COFS3, ERCM2, UVDR, XPG, XPGC
Protein Interaction Partner: UBC, CDK7, GTF2H1, POLR2A, EWSR1, ERCC6, SUMO2, PIDD1, BCL6, TAF10, ERCC3, NTHL1, GTF2H4, PCNA, ERCC2,
Protein Size: 1186

Molecular Weight: 133 kDa

Gene ID: 2073

NCBI Accession: NM_000123, NP_000114

UniProt: P28715

Pathways: DNA Damage Repair