ETFA antibody (N-Term)

Catalog No. ABIN2785636

Product Details anti-ETFA Antibody

Target: ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETFA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FRAAAPGQLR RAASLLRFQS TLVIAEHAND SLAPITLNTI TAATRLGGEV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ETFA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ETFA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 333 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ETFA

Target: ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))

Alternative Name: ETFA (ETFA Products)

Synonyms: 2010200I21Rik antibody, D9Ertd394e antibody, ETF antibody, EMA antibody, GA2 antibody, MADD antibody, cb1020 antibody, fd06h11 antibody, wu:fd06h11 antibody, ema antibody, ga2 antibody, madd antibody, electron transfer flavoprotein alpha subunit antibody, electron-transfer-flavoprotein, alpha polypeptide antibody, putative electron-transfer-flavoprotein,alpha polypeptide antibody, electron transfer flavoprotein subunit alpha, mitochondrial antibody, electron transferring flavoprotein, alpha polypeptide antibody, electron transfer flavoprotein alpha subunit L homeolog antibody, ETFA antibody, Tc00.1047053503559.109 antibody, Tc00.1047053511693.90 antibody, LMJF_28_1140 antibody, LOC100194695 antibody, etfa antibody, Etfa antibody, etfa.L antibody

Background: ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EMA, GA2, MADD
Protein Interaction Partner: SUMO2, MDM2, PSEN1, PPP6R3, BAG3, TPM1, UBC, SORD, HADHA, ETFB, CDC42, HDAC5, MYC, ICT1, UBA5, DDA1, ATG101,
Protein Size: 333

Molecular Weight: 35 kDa

Gene ID: 2108

NCBI Accession: NM_000126, NP_000117

UniProt: P13804

Pathways: SARS-CoV-2 Protein Interactome