IGF2 antibody (C-Term)

Catalog No. ABIN2785661

Product Details anti-IGF2 Antibody

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Pig, Goat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YDTWKQSTQR LRRGLPALLR ARRGHVLAKE LEAFREAKRH RPLIALPTQD

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 93%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 85%, Rat: 92%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against IGF2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 236 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Alternative Name: IGF2 (IGF2 Products)

Synonyms: C11orf43 antibody, IGF-II antibody, PP9974 antibody, LOC100136550 antibody, igf2 antibody, igf2b antibody, wu:fc26e03 antibody, zgc:91781 antibody, igf-2 antibody, insigf antibody, pp9974 antibody, AL033362 antibody, Igf-2 antibody, Igf-II antibody, M6pr antibody, Mpr antibody, Peg2 antibody, IGFII antibody, RNIGF2 antibody, IGF-II-B antibody, igf2-a antibody, igf2-b antibody, insulin like growth factor 2 antibody, insulin-like growth factor II antibody, insulin-like growth factor 2a antibody, insulin like growth factor 2 S homeolog antibody, insulin-like growth factor 2 antibody, insulin-like growth factor 2 (somatomedin A) antibody, insulin like growth factor 2 L homeolog antibody, IGF2 antibody, LOC100136550 antibody, igf2a antibody, igf2.S antibody, Igf2 antibody, igf2.L antibody

Background: This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: C11orf43, FLJ22066, FLJ44734, INSIGF, pp9974, IGF-II, PP9974
Protein Interaction Partner: RBPMS, PCSK4, NMRK2, FAF1, BAG6, IGFBP7, GPC3, VTN, PLG, NOV, INSR, IGF1R, IGF2R, IGFBP6, IGFBP5, IGFBP4, IGFBP3, IGFBP2, IGFBP1, IDE, TF,
Protein Size: 236

Molecular Weight: 25 kDa

Gene ID: 3481

NCBI Accession: NM_001127598, NP_001121070

UniProt: C9JAF2

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation