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NLRP1 antibody (N-Term)

NLRP1 Reactivity: Human, Mouse, Cow, Dog, Horse, Rat, Guinea Pig, Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785731
  • Target See all NLRP1 Antibodies
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    Binding Specificity
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Cow, Dog, Horse, Rat, Guinea Pig, Pig, Rabbit
    Host
    • 35
    • 2
    • 1
    Rabbit
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 17
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP1 antibody is un-conjugated
    Application
    • 28
    • 13
    • 13
    • 11
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DTQEPRIVIL QGAAGIGKST LARQVKEAWG RGQLYGDRFQ HVFYFSCREL
    Predicted Reactivity
    Cow: 85%, Dog: 86%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 85%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against NLRP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human NLRP1
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  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1375 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    Alternative Name
    NLRP1 (NLRP1 Products)
    Synonyms
    CARD7 antibody, CIDED antibody, CLR17.1 antibody, DEFCAP antibody, DEFCAP-L/S antibody, NAC antibody, NALP1 antibody, PP1044 antibody, SLEV1 antibody, VAMAS1 antibody, NLR family pyrin domain containing 1 antibody, NLRP1 antibody, Nlrp1 antibody
    Background
    This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like
    Alias Symbols: CARD7, CLR17.1, DEFCAP, DEFCAP-L/S, DKFZp586O1822, KIAA0926, NAC, NALP1, PP1044, SLEV1, VAMAS1
    Protein Interaction Partner: TRIM68, CUL3, APOA1, NLRP1, PYCARD, NOD1, CASP5, CASP9, APAF1, CASP2, BCL2L1, BCL2, CASP1, NLRC4,
    Protein Size: 1375
    Molecular Weight
    155 kDa
    Gene ID
    22861
    NCBI Accession
    NM_001033053, NP_001028225
    UniProt
    Q9C000
    Pathways
    Positive Regulation of Endopeptidase Activity, Inflammasome
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