ICT1 antibody (Middle Region)
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- Target See all ICT1 Antibodies
- ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Guinea Pig, Rabbit, Cow, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ICT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AEWIAEPVRQ KIAITHKNKI NRLGELILTS ESSRYQFRNL ADCLQKIRDM
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ICT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ICT1
- Top Product
- Discover our top product ICT1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 206 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))
- Alternative Name
- ICT1 (ICT1 Products)
- Synonyms
- ICT1 antibody, DS-1 antibody, DS1 antibody, 1110001A02Rik antibody, 1110002E03Rik antibody, mitochondrial ribosomal protein L58 antibody, imitochondrial ribosomal protein L58 S homeolog antibody, Immature colon carcinoma transcript 1 antibody, MRPL58 antibody, mrpl58.S antibody, PVX_091510 antibody, mrpl58 antibody, Mrpl58 antibody, ict1 antibody
- Background
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The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells.The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells.
Alias Symbols: DS-1, DS1
Protein Interaction Partner: UBC, LIN28A, MRPS6, MRPS27, DAP3, MRPS18B, MRPL3, MRPL12, NPM1, MTHFD1, SYNCRIP, FLOT1, PPT2, RPL14, EIF4H, UQCRFS1, SRSF3, RPS18, RPS15, MRPL23, RPL4, RPL3, NDUFB7, NDUFB5, NDUFA2, ILF2, HNRNPU, CYC1, CLPTM1, CDH2, CALU, APP, ERGIC1, DDX28, SYNJ2BP, MRPL
Protein Size: 206 - Molecular Weight
- 23 kDa
- Gene ID
- 3396
- NCBI Accession
- NM_001545, NP_001536
- UniProt
- Q14197
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