FKBP3 antibody (C-Term)

Catalog No. ABIN2785798

Product Details anti-FKBP3 Antibody

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EALLTMSKGE KARLEIEPEW AYGKKGQPDA KIPPNAKLTF EVELVDID

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against FKBP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FKBP3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 224 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FKBP3

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Alternative Name: FKBP3 (FKBP3 Products)

Synonyms: FKBP3 antibody, 25kDa antibody, FKBP-3 antibody, FKBP25 antibody, FK506 antibody, fb75c04 antibody, si:dz261o22.2 antibody, wu:fb75c04 antibody, zgc:110728 antibody, FKBP-25 antibody, PPIase antibody, FK506 binding protein 3 antibody, FK506 binding protein 3 L homeolog antibody, peptidylprolyl isomerase antibody, FKBP3 antibody, Fkbp3 antibody, fkbp3 antibody, fkbp3.L antibody, CAALFM_C103790CA antibody

Background: FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Alias Symbols: FKBP-25, PPIase, FKBP-3, FKBP25
Protein Interaction Partner: UBC, EDC4, IGF2BP3, SYNCRIP, SEC16A, EIF2B2, EIF2B3, DYNLL1, RFC4, YBX1, NMT1, KRT18, ILF2, HNRNPU, HNRNPA2B1, DDX1, ABCF1, MAP1S, C14orf166, DIMT1, NELFB, SRPK1, FBXO25, BARD1, MYH10, PACSIN3, LRRFIP1, TIMELESS, Nedd4, NEDD4L, CALM1, HDAC2, HDAC1, YY1, C
Protein Size: 224

Molecular Weight: 25 kDa

Gene ID: 2287

NCBI Accession: NM_002013, NP_002004

UniProt: Q00688