HSPA6 antibody (Middle Region)

Catalog No. ABIN2785818

Product Details anti-HSPA6 Antibody

Target: HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))

Binding Specificity: Middle Region

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPA6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EYEHQKRELE QICRPIFSRL YGGPGVPGGS SCGTQARQGD PSTGPIIEEV

Predicted Reactivity: Human: 100%, Pig: 79%

Characteristics: This is a rabbit polyclonal antibody against HSPA6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSPA6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Antigen size: 643 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSPA6

Target: HSPA6 (Heat Shock 70kDa Protein 6 (HSP70B') (HSPA6))

Alternative Name: HSPA6 (HSPA6 Products)

Synonyms: HSPA6 antibody, HSP70B' antibody, heat shock protein family A (Hsp70) member 6 antibody, HSPA6 antibody

Background: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Alias Symbols: -
Protein Interaction Partner: TP53, MLF2, UBC, HSPA1A, HSPA8, HDAC6, ADCK5, CYP4F12, env, DNAJB4, IQCB1, UBL4A, NOS2, CISH, CFTR, TRAF3IP1, HSP90AA1, SCFD1, HSPA5, HSPA1L, SHC1, PIK3R2, INPPL1, CRK, AP2M1, CBL, COPS5, CUL1, NEDD8, TERF1, PARD3, ARRB2, INSIG2, DYRK2, RFWD2, RPAP3, MEPC
Protein Size: 643

Molecular Weight: 71 kDa

Gene ID: 3310

NCBI Accession: NM_002155, NP_002146

UniProt: P17066