LCP1 antibody (N-Term)

Catalog No. ABIN2785830

Product Details anti-LCP1 Antibody

Target: LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LCP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FIKIFHGLKS TDVAKTFRKA INKKEGICAI GGTSEQSSVG TQHSYSEEEK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against LCP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LCP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 627 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LCP1

Target: LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))

Alternative Name: LCP1 (LCP1 Products)

Synonyms: CP64 antibody, L-PLASTIN antibody, LC64P antibody, LPL antibody, PLS2 antibody, cb245 antibody, fj24b12 antibody, wu:fj24b12 antibody, cp64 antibody, l-plastin antibody, lc64p antibody, lpl antibody, pls2 antibody, plastin-2 antibody, AW536232 antibody, D14Ertd310e antibody, LCP-1 antibody, Pls2 antibody, pp65 antibody, lymphocyte cytosolic protein 1 antibody, lymphocyte cytosolic protein 1 (L-plastin) antibody, lymphocyte cytosolic protein 1 (L-plastin) S homeolog antibody, lower matrix protein; involved in immune regulation antibody, LCP1 antibody, lcp1 antibody, lcp1.S antibody, Lcp1 antibody, UL83 antibody

Background: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The L isoform is expressed only in hemopoietic cell lineages. However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CP64, DKFZp781A23186, FLJ25423, FLJ26114, FLJ39956, L-PLASTIN, LC64P, PLS2, LPL
Protein Interaction Partner: UBC, Aif1, FN1, RAD23B, SIRT7, GCA, CNN3, PRKACA, ATXN2, LCP1,
Protein Size: 627

Molecular Weight: 70 kDa

Gene ID: 3936

NCBI Accession: NM_002298, NP_002289

UniProt: P13796