GBP2 antibody (N-Term)

Catalog No. ABIN2785847

Product Details anti-GBP2 Antibody

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HTKGIWMWCV PHPKKPEHTL VLLDTEGLGD IEKGDNENDS WIFALAILLS

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against GBP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GBP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 591 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GBP2

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Alternative Name: GBP2 (GBP2 Products)

Synonyms: guanylate binding protein 2 antibody, guanylate binding protein 2, interferon-inducible antibody, GTP binding protein 2 L homeolog antibody, GBP2 antibody, Gbp2 antibody, gtpbp2.L antibody

Background: GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP2 is a GTPase that converts GTP to GDP and GMP. Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.
Alias Symbols: -
Protein Interaction Partner: CNDP2, NANS, RPS6KA1, PEPD, MVD, GSR, GNS, GLA, G6PD, CASP7, CAPN1, ASS1, GSK3B, GADD45A, CSNK2B, BNIP3L, BID, ANXA7, MAPK8IP2, STK3, KLHL20, BTBD2, LSM2, PAFAH1B3, PPP1R8, MAGI1, TFG, SERPINB9, SEPHS1, FXR1, HSPE1, SAT1,
Protein Size: 591

Molecular Weight: 67 kDa

Gene ID: 2634

NCBI Accession: NM_004120, NP_004111

UniProt: P32456

Pathways: Cellular Response to Molecule of Bacterial Origin