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LOXL1 antibody (Middle Region)

LOXL1 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785879
  • Target See all LOXL1 Antibodies
    LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))
    Binding Specificity
    • 13
    • 7
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 47
    • 21
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Pig, Zebrafish (Danio rerio)
    Host
    • 52
    • 6
    Rabbit
    Clonality
    • 54
    • 4
    Polyclonal
    Conjugate
    • 26
    • 11
    • 10
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LOXL1 antibody is un-conjugated
    Application
    • 34
    • 22
    • 13
    • 10
    • 9
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    YRPNQNGRGL PDLVPDPNYV QASTYVQRAH LYSLRCAAEE KCLASTAYAP
    Predicted Reactivity
    Cow: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against LOXL1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human LOXL1
    Top Product
    Discover our top product LOXL1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 574 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))
    Alternative Name
    LOXL1 (LOXL1 Products)
    Synonyms
    LOL antibody, LOXL antibody, Loxl antibody, si:ch211-238c15.1 antibody, lol antibody, loxl antibody, loxl-1 antibody, oxl-1 antibody, lysyl oxidase like 1 antibody, lysyl oxidase-like 1 antibody, lysyl oxidase like 1 L homeolog antibody, LOXL1 antibody, loxl1 antibody, Loxl1 antibody, loxl1.L antibody
    Background
    LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: LOL, LOXL
    Protein Interaction Partner: ATXN1, CUL2, FBLN5, ELN,
    Protein Size: 574
    Molecular Weight
    53 kDa
    Gene ID
    4016
    NCBI Accession
    NM_005576, NP_005567
    UniProt
    Q08397
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