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PHGDH antibody (Middle Region)

PHGDH Reactivity: Human, Mouse, Rat, Horse, Pig, Rabbit, Dog, Cow, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785892
  • Target See all PHGDH Antibodies
    PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
    Binding Specificity
    • 15
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Horse, Pig, Rabbit, Dog, Cow, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 52
    • 6
    • 1
    Rabbit
    Clonality
    • 54
    • 5
    Polyclonal
    Conjugate
    • 26
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHGDH antibody is un-conjugated
    Application
    • 49
    • 23
    • 18
    • 13
    • 13
    • 12
    • 11
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    CAGAALDVFT EEPPRDRALV DHENVISCPH LGASTKEAQS RCGEEIAVQF
    Predicted Reactivity
    Cow: 93%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against PHGDH. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PHGDH
    Top Product
    Discover our top product PHGDH Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 533 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
    Alternative Name
    PHGDH (PHGDH Products)
    Synonyms
    fb38f06 antibody, zgc:65956 antibody, wu:fb38f06 antibody, embryo sac development arrest 9 antibody, F10M10.7 antibody, ECK2909 antibody, JW2880 antibody, 3-PGDH antibody, 3PGDH antibody, 4930479N23 antibody, A10 antibody, PGAD antibody, PGD antibody, PGDH antibody, SERA antibody, PDG antibody, phosphoglycerate dehydrogenase antibody, D-3-phosphoglycerate dehydrogenase antibody, 3-phosphoglycerate dehydrogenase antibody, phgdh antibody, EDA9 antibody, serA antibody, Sthe_2284 antibody, Dacet_1260 antibody, Mrub_0173 antibody, MMAH_RS07650 antibody, Arnit_0487 antibody, Ndas_0174 antibody, Mesil_2386 antibody, Slip_0010 antibody, Trad_0302 antibody, Acear_0027 antibody, Mahau_0665 antibody, MZHIL_RS05165 antibody, Mesop_1331 antibody, Thein_0855 antibody, Phgdh antibody, PHGDH antibody
    Background
    3-Phosphoglycerate dehydrogenase (PHGDH) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.3-Phosphoglycerate dehydrogenase (PHGDH, EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.[supplied by OMIM].
    Alias Symbols: 3-PGDH, 3PGDH, MGC3017, PDG, PGAD, PGD, PGDH, SERA
    Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, ITSN1, ROM1, RPAP3, EPN1, SUMO1, NEDD8, MDM2, SUZ12, RNF2, EZH2, BMI1, FBXO6, TARDBP, EGFR, UBD, CLN5, CLN3, CDK2, PIAS4, FN1, TRAF3IP1, ECT2, MDC1, UQCC3, VASN, TRIM55, SMU1, TRA2A, ADNP, NCSTN, U2AF2, TCERG1, UTP14A, SRSF10, SAP1
    Protein Size: 533
    Molecular Weight
    57 kDa
    Gene ID
    26227
    NCBI Accession
    NM_006623, NP_006614
    UniProt
    O43175
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Warburg Effect
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