PNMA3 antibody (Middle Region)

Catalog No. ABIN2785969

Product Details anti-PNMA3 Antibody

Target: PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNMA3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RITGVGAVPL PASGNSFDVR PSQGYRRRRG RGQHRRGGVA RAGSRGSRKR

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PNMA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PNMA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 463 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PNMA3

Target: PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))

Alternative Name: PNMA3 (PNMA3 Products)

Synonyms: MA3 antibody, MA5 antibody, RGD1563752 antibody, PNMA family member 3 antibody, paraneoplastic antigen MA3 antibody, paraneoplastic Ma antigen 3 antibody, PNMA3 antibody, Pnma3 antibody

Background: The specific function of the protein remains unknown.This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized.
Alias Symbols: MA3, MA5, MGC132756, MGC132758
Protein Interaction Partner: PARD6G,
Protein Size: 463

Molecular Weight: 52 kDa

Gene ID: 29944

NCBI Accession: NM_013364, NP_037496

UniProt: Q9UL41