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ORC6 antibody (C-Term)

ORC6 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786008
  • Target See all ORC6 Antibodies
    ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
    Binding Specificity
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig
    Host
    • 21
    • 6
    • 2
    • 1
    Rabbit
    Clonality
    • 24
    • 6
    Polyclonal
    Conjugate
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ORC6 antibody is un-conjugated
    Application
    • 21
    • 8
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    VEAPAKEMEK VEEMPHKPQK DEDLTQDYEE WKRKILENAA SAQKATAE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against ORC6L. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ORC6L
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    Discover our top product ORC6 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 252 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
    Alternative Name
    ORC6L (ORC6 Products)
    Synonyms
    Orc6l antibody, CG1584 antibody, DmORC 6 antibody, DmORC6 antibody, Dmel\\CG1584 antibody, ORC antibody, ORC6 antibody, orc6 antibody, rDmORC antibody, ORC6L antibody, ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 antibody, ATORC6 antibody, ORIGIN RECOGNITION COMPLEX SUBUNIT 6 antibody, T2P11.3 antibody, T2P11_3 antibody, origin recognition complex protein 6 antibody, DDBDRAFT_0186183 antibody, DDBDRAFT_0233113 antibody, DDB_0186183 antibody, DDB_0233113 antibody, LOC100284755 antibody, orc6l antibody, 6720420I10Rik antibody, origin recognition complex, subunit 6 antibody, Origin recognition complex subunit 6 antibody, origin recognition complex subunit 6 antibody, origin recognition complex protein 6 antibody, origin recognition complex subunit Orc6 antibody, Orc6 antibody, ORC6 antibody, CpipJ_CPIJ005016 antibody, SJAG_01267 antibody, orcF antibody, LOC100284755 antibody, orc6 antibody
    Background
    The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC6L is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ORC6, ORC6L
    Protein Interaction Partner: LHX4, SPAG5, UBC, ORC3, CDC7, ORC4, MCM7, MCM6, MCM4, MCM2, CDC6, APP, ORC2, SUMO2, XRCC5, XRCC6, HMGA1, MCM5, TERF2, ORC5, DBF4, CDC45, RPA1,
    Protein Size: 252
    Molecular Weight
    28 kDa
    Gene ID
    23594
    NCBI Accession
    NM_014321, NP_055136
    UniProt
    Q9Y5N6
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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