SENP1 antibody (Middle Region)
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- Target See all SENP1 Antibodies
- SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SENP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PQQMNGSDCG MFACKYADCI TKDRPINFTQ QHMPYFRKRM VWEILHRKLL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
- Characteristics
- This is a rabbit polyclonal antibody against SENP1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SENP1
- Top Product
- Discover our top product SENP1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 643 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
- Alternative Name
- SENP1 (SENP1 Products)
- Synonyms
- SuPr-2 antibody, 2310046A20Rik antibody, D15Ertd528e antibody, E330036L07Rik antibody, suPr-2 antibody, senp1 antibody, senp1a antibody, xsenp1 antibody, SENP1 antibody, Senp1 antibody, senp1b antibody, SUMO1/sentrin specific peptidase 1 antibody, SUMO1/sentrin specific peptidase 1 S homeolog antibody, sentrin/SUMO-specific protease 1 antibody, SUMO1/sentrin specific peptidase 1 L homeolog antibody, SENP1 antibody, Senp1 antibody, senp1.S antibody, senp1.L antibody, senp1 antibody
- Background
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The covalent modification of proteins by the small ubiquitin-like protein SUMO is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1.
Alias Symbols: SuPr-2
Protein Interaction Partner: USP25, RABGAP1, SUMO1, TP53, SP100, SUMO2, SUMO3, RANGAP1, PRDM1, BAG3, LMNA, APP, UBD, U90, HIPK2, ISG15, RANBP2, HDAC2, ELAVL1, UBC, GCM1, RUVBL2, HDAC1, PARP1, HDAC4, KCNK1, SENP1, SP3,
Protein Size: 643 - Molecular Weight
- 73 kDa
- Gene ID
- 29843
- NCBI Accession
- NM_014554, NP_055369
- Pathways
- Positive Regulation of Endopeptidase Activity
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