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SENP1 antibody (Middle Region)

SENP1 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786045
  • Target See all SENP1 Antibodies
    SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
    Binding Specificity
    • 11
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 66
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 77
    • 2
    Rabbit
    Clonality
    • 70
    • 9
    Polyclonal
    Conjugate
    • 32
    • 8
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SENP1 antibody is un-conjugated
    Application
    • 60
    • 45
    • 23
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PQQMNGSDCG MFACKYADCI TKDRPINFTQ QHMPYFRKRM VWEILHRKLL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
    Characteristics
    This is a rabbit polyclonal antibody against SENP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SENP1
    Top Product
    Discover our top product SENP1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 643 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
    Alternative Name
    SENP1 (SENP1 Products)
    Synonyms
    SuPr-2 antibody, 2310046A20Rik antibody, D15Ertd528e antibody, E330036L07Rik antibody, suPr-2 antibody, senp1 antibody, senp1a antibody, xsenp1 antibody, SENP1 antibody, Senp1 antibody, senp1b antibody, SUMO1/sentrin specific peptidase 1 antibody, SUMO1/sentrin specific peptidase 1 S homeolog antibody, sentrin/SUMO-specific protease 1 antibody, SUMO1/sentrin specific peptidase 1 L homeolog antibody, SENP1 antibody, Senp1 antibody, senp1.S antibody, senp1.L antibody, senp1 antibody
    Background
    The covalent modification of proteins by the small ubiquitin-like protein SUMO is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1.
    Alias Symbols: SuPr-2
    Protein Interaction Partner: USP25, RABGAP1, SUMO1, TP53, SP100, SUMO2, SUMO3, RANGAP1, PRDM1, BAG3, LMNA, APP, UBD, U90, HIPK2, ISG15, RANBP2, HDAC2, ELAVL1, UBC, GCM1, RUVBL2, HDAC1, PARP1, HDAC4, KCNK1, SENP1, SP3,
    Protein Size: 643
    Molecular Weight
    73 kDa
    Gene ID
    29843
    NCBI Accession
    NM_014554, NP_055369
    Pathways
    Positive Regulation of Endopeptidase Activity
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