TBC1D1 antibody (Middle Region)

Catalog No. ABIN2786087

Product Details anti-TBC1D1 Antibody

Target: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBC1D1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RGSPGVSQRK LMRYHSVSTE TPHERKDFES KANHLGDSGG TPVKTRRHSW

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TBC1D1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBC1D1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1168 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TBC1D1

Target: TBC1D1 (TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1))

Alternative Name: TBC1D1 (TBC1D1 Products)

Synonyms: TBC1D1 antibody, TBC antibody, TBC1 antibody, 1110062G02Rik antibody, AI385682 antibody, AW555803 antibody, Tbc1 antibody, mKIAA1108 antibody, TBC1 domain family member 1 antibody, TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 antibody, TBC1 domain family, member 1 antibody, TBC1D1 antibody, tbc1d1 antibody, LOC100523386 antibody, Tbc1d1 antibody

Background: TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6), yeast Bub2, and CDC16.TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6, MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-225 BC050321.1 13-237 226-950 BC050321.1 896-1620 951-1020 BC028196.1 226-295 1021-1123 BC029950.1 255-357 1124-1433 BC028196.1 399-708 1434-1608 BC029950.1 668-842 1609-4133 BC053648.1 437-2961 4134-5688 AK074954.1 1433-2987
Alias Symbols: KIAA1108, TBC, TBC1
Protein Interaction Partner: UBC, YWHAB, YWHAE, ROR1, SMAD2, BARD1, MAP1LC3A, GABARAPL1, YWHAG,
Protein Size: 1168

Molecular Weight: 133 kDa

Gene ID: 23216

NCBI Accession: NM_015173, NP_055988

UniProt: Q86TI0