SAMHD1 antibody (Middle Region)

Catalog No. ABIN2786114

Product Details anti-SAMHD1 Antibody

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Goat, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMHD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KGRPENKSFL YEIVSNKRNG IDVDKWDYFA RDCHHLGIQN NFDYKRFIKF

Predicted Reactivity: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against SAMHD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SAMHD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 626 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Alternative Name: SAMHD1 (SAMHD1 Products)

Synonyms: CHBL2 antibody, DCIP antibody, HDDC1 antibody, MOP-5 antibody, SBBI88 antibody, si:dkeyp-44b8.8 antibody, E330031J07Rik antibody, Mg11 antibody, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 antibody, SAM domain and HD domain 1 antibody, SAM domain and HD domain, 1 antibody, SAMHD1 antibody, samhd1 antibody, Samhd1 antibody

Background: SAMHD1 contains 1 HD domain and 1 SAM (sterile alpha motif) domain. SAMHD1 may play a role in mediating proinflammatory responses to TNF-alpha signaling.
Alias Symbols: AGS5, DCIP, HDDC1, MOP-5, SBBI88, CHBL2
Protein Interaction Partner: SUMO2, SKP2, CDK2, CDK1, CCNA2, HSF5, SUMO1, UBC, NEDD8, RNF2, TRMT1, GANAB, XPO7, FAF1, HSPH1, SEC23A, PRMT3, RANBP3, SF1, XRCC5, TUBG1, SUPT5H, RPL24, PLOD2, OSBP, NARS, JUP, MSH6, GART, XRCC6, EIF4B, ATP6V1E1, FBXO25, KPNB1, vpx, RBX1, CD81, BARD1, APP
Protein Size: 626

Molecular Weight: 72 kDa

Gene ID: 25939

NCBI Accession: NM_015474, NP_056289

UniProt: Q9Y3Z3