SH2B1 antibody (Middle Region)

Catalog No. ABIN2786119

Product Details anti-SH2B1 Antibody

Target: SH2B1 (SH2B Adaptor Protein 1 (SH2B1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GTSFLTRENT DSLELSCLNH SESLPSQDLL LGPSESNDRL SQGAYGGLSD

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SH2B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SH2B1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 671 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SH2B1

Target: SH2B1 (SH2B Adaptor Protein 1 (SH2B1))

Alternative Name: SH2B1 (SH2B1 Products)

Synonyms: zgc:158474 antibody, SH2B3 antibody, PSM antibody, SH2B antibody, AI425885 antibody, C530001K22Rik antibody, Irip antibody, SH2-B antibody, SH2-Bb antibody, Sh2bpsm1 antibody, mKIAA1299 antibody, Sh2-b antibody, Sh2b antibody, SH2B adaptor protein 1 antibody, SH2B1 antibody, sh2b1 antibody, Sh2b1 antibody

Background: SH2B1 is a member of the SH2-domain containing mediators family. SH2B1 mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation.
Alias Symbols: DKFZp547G1110, FLJ30542, SH2-B, SH2B, PSM
Protein Interaction Partner: FGFR3, SH2B1, SH2B2, JAK2, INSR, IGF1R, RHBG, EGFR, IRS1, BRCA1, KIAA0319, NTRK2, NTRK1, GRB2,
Protein Size: 671

Molecular Weight: 71 kDa

Gene ID: 25970

NCBI Accession: NM_015503, NP_056318