HSPA2 antibody (Middle Region)

Catalog No. ABIN2786177

Product Details anti-HSPA2 Antibody

Target: HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Goat, Pig, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ITITNDKGRL SKDDIDRMVQ EAERYKSEDE ANRDRVAAKN ALESYTYNIK

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HSPA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSPA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 639 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSPA2

Target: HSPA2 (Heat Shock 70kDa Protein 2 (HSPA2))

Alternative Name: HSPA2 (HSPA2 Products)

Synonyms: HSP70-2 antibody, HSP70-3 antibody, HSPA2 antibody, DKFZp468B217 antibody, 70kDa antibody, HSP70.2 antibody, HSP70A2 antibody, Hsp70-2 antibody, Hspt70 antibody, Hst70 antibody, HSPA3 antibody, heat shock protein family A (Hsp70) member 2 antibody, heat shock protein Hsp20 antibody, heat shock 70kDa protein 2 antibody, heat shock protein 2 antibody, heat shock protein family A member 2 antibody, HSPA2 antibody, hspA2 antibody, Hspa2 antibody

Background: HSPA2 belongs to the heat shock protein 70 family.In cooperation with other chaperones, HSPA2 stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Alias Symbols: HSP70-2, HSP70-3
Protein Interaction Partner: HSPBP1, TRIM38, TP53, UBC, CEP76, HAUS2, CEP250, SAE1, CEP57, AURKA, SUMO2, SUMO3, CDKN1A, STUB1, BAG4, HSPA8, LGR4, PARK2, EGFR, BAG3, HDAC6, UBL4A, PPP1CC, NOS2, CFTR, METTL21B, METTL21A, MAP1LC3A, HSP90AA1, HSPA1A, EEF1A1, APP, MEOX2, EWSR1, FBXO25, SI
Protein Size: 639

Molecular Weight: 70 kDa

Gene ID: 3306

NCBI Accession: NM_021979, NP_068814

UniProt: P54652