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APBB2 antibody (Middle Region)

APBB2 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786292
  • Target See all APBB2 Antibodies
    APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))
    Binding Specificity
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 38
    • 16
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse, Pig
    Host
    • 36
    • 2
    Rabbit
    Clonality
    • 37
    • 1
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APBB2 antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    QNLAPSDEES SWTTLSQDSA SPSSPDETDI WSDHSFQTDP DLPPGWKRVS
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against APBB2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human APBB2
    Top Product
    Discover our top product APBB2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 736 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hong, Hsu, Schultz, Pratt, Mattison, Chang: "Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response." in: BMC molecular biology, Vol. 8, pp. 50, (2007) (PubMed).

  • Target
    APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))
    Alternative Name
    APBB2 (APBB2 Products)
    Synonyms
    FE65L antibody, FE65L1 antibody, 2310007D03Rik antibody, Rirl1 antibody, TR2L antibody, Zfra antibody, RGD1562438 antibody, APBB2 antibody, fe65l antibody, fe65l1 antibody, DKFZp469I236 antibody, si:ch211-201g8.2 antibody, amyloid beta precursor protein binding family B member 2 antibody, amyloid beta (A4) precursor protein-binding, family B, member 2 antibody, amyloid beta (A4) precursor protein-binding, family B, member 2b antibody, APBB2 antibody, Apbb2 antibody, apbb2 antibody, apbb2b antibody
    Background
    APBB2 may modulate the internalization of beta-amyloid precursor protein.The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction.
    Alias Symbols: FE65L, FE65L1, MGC35575
    Protein Interaction Partner: UBC, EGFR, SMURF1, SMAD4, APLP2, APP,
    Protein Size: 736
    Molecular Weight
    81 kDa
    Gene ID
    323
    NCBI Accession
    NM_173075, NP_775098
    UniProt
    Q92870
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