AMIGO2 antibody (N-Term)

Catalog No. ABIN2786380

Product Details anti-AMIGO2 Antibody

Target: AMIGO2 (Adhesion Molecule with Ig-Like Domain 2 (AMIGO2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMIGO2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSYNRIGLLD SEWIPVSFAK LNTLILRHNN ITSISTGSFS TTPNLKCLDL

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against AMIGO2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human AMIGO2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AMIGO2

Target: AMIGO2 (Adhesion Molecule with Ig-Like Domain 2 (AMIGO2))

Alternative Name: AMIGO2 (AMIGO2 Products)

Synonyms: AMIGO2 antibody, AI415330 antibody, AMIGO-2 antibody, AW208913 antibody, Ali1 antibody, ALI1 antibody, DEGA antibody, adhesion molecule with Ig like domain 2 antibody, adhesion molecule with Ig-like domain 2 antibody, AMIGO2 antibody, Amigo2 antibody

Background: AMIGO2 is required for depolarization-dependent survival of cultured cerebellar granule neurons. It may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3 abd may contribute to signal transduction through its intracellular domain. It also may be required for tumorigenesis of a subset of gastric adenocarcinomas.
Alias Symbols: ALI1, AMIGO-2, DEGA
Protein Interaction Partner: UBC, CACNA1A, AMIGO3, AMIGO2, AMIGO1,
Protein Size: 522

Molecular Weight: 58 kDa

Gene ID: 347902

NCBI Accession: NM_181847, NP_862830

UniProt: Q86SJ2