SPDYA antibody (Middle Region)

Catalog No. ABIN2786399

Product Details anti-SPDYA Antibody

Target: SPDYA (Speedy Homolog A (SPDYA))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPDYA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HTAGVTEKHS QDSYNSLSMD IIGDPSQAYT GSEVVNDHQS NKGKKTNFLK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SPDYA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPDYA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 313 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPDYA

Target: SPDYA (Speedy Homolog A (SPDYA))

Alternative Name: SPDYA (SPDYA Products)

Synonyms: zgc:101624 antibody, 4921517J08Rik antibody, 4930548B21Rik antibody, GS4 antibody, MLZ-465 antibody, Spdy1 antibody, RINGO antibody, SPDY1 antibody, RINGO3 antibody, RINGOA antibody, SPY1 antibody, Gs4 antibody, Lm23 antibody, Spy1 antibody, speedy homolog A (Xenopus laevis) antibody, speedy/RINGO cell cycle regulator family member A antibody, speedy/RINGO cell cycle regulator family, member A antibody, SPDYA antibody, spdya antibody, Spdya antibody

Background: SPDYA regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
Alias Symbols: MGC110856, MGC57218, SPDY1, SPY1, RINGO3, RINGOA
Protein Interaction Partner: CDK2, UBC, SKP2, CDKN1B,
Protein Size: 313

Molecular Weight: 36 kDa

Gene ID: 245711

NCBI Accession: NM_182756, NP_877433

UniProt: Q5MJ70