SS18L1 antibody (Middle Region)

Catalog No. ABIN2786440

Product Details anti-SS18L1 Antibody

Target: SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SS18L1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EYYGEQYSHS QGAAEPMGQQ YYPDGHGDYA YQQSSYTEQS YDRSFEESTQ

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SS18L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SS18L1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 396 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SS18L1 antibody (ABIN2786440)

de Bruijn, Geurts van Kessel: "Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci." in: Cytogenetic and genome research, Vol. 112, Issue 3-4, pp. 222-6, (2006) (PubMed).

Target Details for SS18L1

Target: SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))

Alternative Name: SS18L1 (SS18L1 Products)

Synonyms: crest antibody, CREST antibody, LP2261 antibody, A230053O16Rik antibody, SS18L1, nBAF chromatin remodeling complex subunit antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, synovial sarcoma translocation gene on chromosome 18-like 1 S homeolog antibody, SS18, nBAF chromatin remodeling complex subunit like 1 antibody, SS18L1 antibody, ss18l1 antibody, ss18l1.S antibody, Ss18l1 antibody

Background: The specific functin of this protein remains unknown.Synovial sarcomas occur most frequently in the extremities around large joints. More than 90 % of cases have a recurrent and specific chromosomal translocation, t(X,18)(p11.2,q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to SS18.[supplied by OMIM].
Alias Symbols: CREST, KIAA0693, LP2261, MGC26711, MGC78386
Protein Interaction Partner: MAPK1IP1L, SS18L1, FAM168A, SF3B4, LGALS3, CSTF2, SNRPC, SNRPB, CTAGE5, DGCR6, BMI1, CUL3, SKA3, ANKRD22, MED30, PCGF6, GATAD1, TAF9B, RLIM, AATF, BRD1, NR1H3, HDAC4, TCF7, STAT3, SMAD3, SMAD1, HDAC2, ELF5, ATF3, SMARCA4, USP30, RFX6, EP300, CREBBP,
Protein Size: 396

Molecular Weight: 43 kDa

Gene ID: 26039

NCBI Accession: NM_198935, NP_945173

UniProt: O75177