VPS54 antibody (N-Term)

Catalog No. ABIN2786552

Product Details anti-VPS54 Antibody

Target: VPS54 (Vacuolar Protein Sorting 54 Homolog (VPS54))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS54 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FNSVLPWSHF NTAGGKGNRD AASSKLLQEK LSHYLDIVEV NIAHQISLRS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against VPS54. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VPS54

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 977 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VPS54

Target: VPS54 (Vacuolar Protein Sorting 54 Homolog (VPS54))

Alternative Name: VPS54 (VPS54 Products)

Synonyms: 5330404P15Rik antibody, Hcc8 antibody, Vps54l antibody, mSLP8 antibody, wr antibody, HCC8 antibody, SLP-8p antibody, VPS54L antibody, WR antibody, hVps54L antibody, Vsp54 antibody, Vacuolar protein sorting-associated protein 54 antibody, VPS54 GARP complex subunit antibody, VPS54, GARP complex subunit antibody, vps-54 antibody, Vps54 antibody, VPS54 antibody

Background: VPS54 may be involved in retrograde transport from early and late endosomes to late Golgi. This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: HCC8, SLP-8p, VPS54L, hVps54L
Protein Interaction Partner: PPP1CA, VPS53, STX6, VPS52, VPS51,
Protein Size: 977

Molecular Weight: 107 kDa

Gene ID: 51542

NCBI Accession: NM_016516, NP_057600

UniProt: Q9P1Q0