PAIP2 antibody (N-Term)

Catalog No. ABIN2786594

Product Details anti-PAIP2 Antibody

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MKDPSRSSTS PSIINEDVII NGHSHEDDNP FAEYMWMENE EEFNRQIEEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PAIP2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 127 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAIP2

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Alternative Name: PAIP2 (PAIP2 Products)

Synonyms: PAIP2A antibody, DKFZp469O1314 antibody, 2310050K10Rik antibody, AU045972 antibody, paip2 antibody, poly(A) binding protein interacting protein 2 antibody, polyadenylate-binding protein-interacting protein 2 antibody, poly(A) binding protein interacting protein 2B L homeolog antibody, PAIP2 antibody, Paip2 antibody, paip2b.L antibody

Background: PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. It displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Alias Symbols: MGC72018, PAIP2A
Protein Interaction Partner: PABPC1, BAG3, RPL11, IGBP1, APP, UBC, UBR5, ELAVL1,
Protein Size: 127

Molecular Weight: 14 kDa

Gene ID: 51247

NCBI Accession: NM_016480, NP_057564

UniProt: Q9BPZ3