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PSMB3 antibody (Middle Region)

PSMB3 Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Horse, Saccharomyces cerevisiae, Goat, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786717
  • Target See all PSMB3 Antibodies
    PSMB3 (Proteasome Subunit beta 3 (PSMB3))
    Binding Specificity
    • 5
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio), Horse, Saccharomyces cerevisiae, Goat, Guinea Pig
    Host
    • 28
    • 3
    • 1
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMB3 antibody is un-conjugated
    Application
    • 32
    • 13
    • 6
    • 5
    • 4
    • 3
    Western Blotting (WB)
    Sequence
    LNLYELKEGR QIKPYTLMSM VANLLYEKRF GPYYTEPVIA GLDPKTFKPF
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against PSMB3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PSMB3
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    Discover our top product PSMB3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 205 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    PSMB3 (Proteasome Subunit beta 3 (PSMB3))
    Alternative Name
    PSMB3 (PSMB3 Products)
    Synonyms
    HC10-II antibody, AL033320 antibody, C10-II antibody, PSB3 antibody, psmb3 antibody, wu:fb11d10 antibody, wu:fu88b08 antibody, zgc:56374 antibody, DDBDRAFT_0190542 antibody, DDBDRAFT_0232932 antibody, DDB_0190542 antibody, DDB_0232932 antibody, proteasome subunit beta 3 antibody, proteasome (prosome, macropain) subunit, beta type 3 antibody, proteasome subunit C10-11 antibody, proteasome subunit beta type-3 antibody, proteasome subunit beta 3 S homeolog antibody, 20S proteasome subunit beta-3 antibody, PSMB3 antibody, Psmb3 antibody, LOC100135869 antibody, LOC399377 antibody, psmb3.S antibody, psmb3 antibody, psmB3 antibody
    Background
    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: HC10-II, MGC4147
    Protein Interaction Partner: UBC, TRIM27, PSMD14, PSMG3, POMP, AP3M1, PSME4, SART3, PSMB7, PSMB6, PSMB5, PSMB4, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PYCRL, PSMA3, PSMA1, KIF5B, EPB41L1, CAST, HECW2, TP53, PSMA2, PARK2, BAG3, MPZ, PRMT2, FN1, CFTR, IQCB1, PSMD13, PSMD12, PSMD11,
    Protein Size: 205
    Molecular Weight
    23 kDa
    Gene ID
    5691
    NCBI Accession
    NM_002795, NP_002786
    UniProt
    P49720
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Cell RedoxHomeostasis, Lipid Metabolism
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