NDUFS3 antibody (Middle Region)
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- Target See all NDUFS3 Antibodies
- NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NDUFS3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EVKRVVAEPV ELAQEFRKFD LNSPWEAFPV YRQPPESLKL EAGDKKPDAK
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against NDUFS3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NDUFS3
- Top Product
- Discover our top product NDUFS3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 264 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))
- Alternative Name
- NDUFS3 (NDUFS3 Products)
- Synonyms
- CI-30 antibody, 0610010M09Rik antibody, CI-30kD antibody, GB15355 antibody, zgc:112520 antibody, NADH:ubiquinone oxidoreductase core subunit S3 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 3 antibody, NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial antibody, NADH:ubiquinone oxidoreductase core subunit S3 S homeolog antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 3, (NADH-coenzyme Q reductase) antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) antibody, NDUFS3 antibody, Ndufs3 antibody, ndufs3 antibody, LOC411411 antibody, ndufs3.S antibody, LOC100228726 antibody
- Background
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This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.
Alias Symbols: CI-30
Protein Interaction Partner: HUWE1, UBC, PARK2, ADRB2, ILK, RASL10B, VCAM1, ITGA4, FN1, Htt, NDUFS7, TMEM14C, SAMM50, MRPL3, SURF1, SSBP1, SLC3A2, SDHA, NDUFV2, NDUFS8, NDUFV1, NDUFS2, NDUFA5, PARK7, CUL3, NDUFB6, NDUFA9, ND6, GZMA, MYC, ICT1,
Protein Size: 264 - Molecular Weight
- 30 kDa
- Gene ID
- 4722
- NCBI Accession
- NM_004551, NP_004542
- UniProt
- O75489
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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