PRKRIR antibody (N-Term)
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- Target See all PRKRIR Antibodies
- PRKRIR (Protein-Kinase, Interferon-Inducible Double Stranded RNA Dependent Inhibitor, Repressor of (p58 Repressor) (PRKRIR))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Horse, Rabbit, Cow, Guinea Pig, Dog, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRKRIR antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VENCRRADLE DKTPDQLNKH YRLCAKHFET SMICRTSPYR TVLRDNAIPT
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against PRKRIR. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRKRIR
- Top Product
- Discover our top product PRKRIR Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 761 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PRKRIR (Protein-Kinase, Interferon-Inducible Double Stranded RNA Dependent Inhibitor, Repressor of (p58 Repressor) (PRKRIR))
- Alternative Name
- PRKRIR (PRKRIR Products)
- Synonyms
- DAP4 antibody, P52rIPK antibody, THAP0 antibody, THAP12 antibody, 2900052B10Rik antibody, Dap4 antibody, Rpkrir antibody, dap4 antibody, p52ripk antibody, MGC75860 antibody, PRKRIR antibody, prkrir antibody, prkrir.S antibody, THAP domain containing 12 antibody, THAP domain containing 12 S homeolog antibody, THAP12 antibody, Thap12 antibody, thap12 antibody, thap12.S antibody
- Background
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PRKRIR is upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). PRKRIR may block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
Alias Symbols: DAP4, MGC102750, P52rIPK, THAP0
Protein Interaction Partner: TACC1, PASK, STK4, STK3, UBC, DDX58, PRKRIR, EIF2S1, DNAJC3, EIF2AK2, TP53,
Protein Size: 761 - Molecular Weight
- 88 kDa
- Gene ID
- 5612
- NCBI Accession
- NM_004705, NP_004696
- UniProt
- O43422
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