PRKRIR antibody (N-Term)

Catalog No. ABIN2786788

Product Details anti-PRKRIR Antibody

Target: PRKRIR (Protein-Kinase, Interferon-Inducible Double Stranded RNA Dependent Inhibitor, Repressor of (p58 Repressor) (PRKRIR))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Guinea Pig, Dog, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKRIR antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VENCRRADLE DKTPDQLNKH YRLCAKHFET SMICRTSPYR TVLRDNAIPT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PRKRIR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRKRIR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 761 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRKRIR

Target: PRKRIR (Protein-Kinase, Interferon-Inducible Double Stranded RNA Dependent Inhibitor, Repressor of (p58 Repressor) (PRKRIR))

Alternative Name: PRKRIR (PRKRIR Products)

Synonyms: DAP4 antibody, P52rIPK antibody, THAP0 antibody, THAP12 antibody, 2900052B10Rik antibody, Dap4 antibody, Rpkrir antibody, dap4 antibody, p52ripk antibody, MGC75860 antibody, PRKRIR antibody, prkrir antibody, prkrir.S antibody, THAP domain containing 12 antibody, THAP domain containing 12 S homeolog antibody, THAP12 antibody, Thap12 antibody, thap12 antibody, thap12.S antibody

Background: PRKRIR is upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). PRKRIR may block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
Alias Symbols: DAP4, MGC102750, P52rIPK, THAP0
Protein Interaction Partner: TACC1, PASK, STK4, STK3, UBC, DDX58, PRKRIR, EIF2S1, DNAJC3, EIF2AK2, TP53,
Protein Size: 761

Molecular Weight: 88 kDa

Gene ID: 5612

NCBI Accession: NM_004705, NP_004696

UniProt: O43422