NDUFS1 antibody (Middle Region)
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- Target See all NDUFS1 Antibodies
- NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Mouse, Cow, Rabbit, Dog, Horse, Goat, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NDUFS1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TPPGLAREDW KIIRALSEIA GMTLPYDTLD QVRNRLEEVS PNLVRYDDIE
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against NDUFS1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NDUFS1
- Top Product
- Discover our top product NDUFS1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 727 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
- Alternative Name
- NDUFS1 (NDUFS1 Products)
- Synonyms
- 5830412M15Rik antibody, 9930026A05Rik antibody, CI-75Kd antibody, CI-75k antibody, PRO1304 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 1 antibody, NADH:ubiquinone oxidoreductase core subunit S1 antibody, Ndufs1 antibody, NDUFS1 antibody
- Background
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The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency.
Alias Symbols: CI-75Kd, MGC26839, PRO1304, CI-75k
Protein Interaction Partner: SUMO2, HSFY1, UBC, MDM2, RNF2, KDM1A, FBXO6, VCAM1, BTK, Htt, NDUFS7, RHOT2, NDUFA12, TMEM126B, MRPL13, STX12, SEC24C, SDHB, RPL27, RAB5B, OPA1, NDUFV3, NDUFV2, NDUFS8, NDUFV1, NDUFS2, NDUFB10, NDUFB9, NDUFB5, NDUFA9, CPT1A, ATP5C1, ATP5B, CUL3, SIRT7, MY
Protein Size: 727 - Molecular Weight
- 77 kDa
- Gene ID
- 4719
- NCBI Accession
- NM_005006, NP_004997
- UniProt
- P28331
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