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NDUFS1 antibody (Middle Region)

NDUFS1 Reactivity: Human, Rat, Mouse, Cow, Rabbit, Dog, Horse, Goat, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786794
  • Target See all NDUFS1 Antibodies
    NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
    Binding Specificity
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 52
    • 34
    • 23
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow, Rabbit, Dog, Horse, Goat, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 47
    • 4
    • 1
    Rabbit
    Clonality
    • 50
    • 2
    Polyclonal
    Conjugate
    • 31
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NDUFS1 antibody is un-conjugated
    Application
    • 43
    • 16
    • 14
    • 13
    • 13
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    TPPGLAREDW KIIRALSEIA GMTLPYDTLD QVRNRLEEVS PNLVRYDDIE
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against NDUFS1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human NDUFS1
    Top Product
    Discover our top product NDUFS1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 727 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))
    Alternative Name
    NDUFS1 (NDUFS1 Products)
    Synonyms
    5830412M15Rik antibody, 9930026A05Rik antibody, CI-75Kd antibody, CI-75k antibody, PRO1304 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 1 antibody, NADH:ubiquinone oxidoreductase core subunit S1 antibody, Ndufs1 antibody, NDUFS1 antibody
    Background
    The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency.
    Alias Symbols: CI-75Kd, MGC26839, PRO1304, CI-75k
    Protein Interaction Partner: SUMO2, HSFY1, UBC, MDM2, RNF2, KDM1A, FBXO6, VCAM1, BTK, Htt, NDUFS7, RHOT2, NDUFA12, TMEM126B, MRPL13, STX12, SEC24C, SDHB, RPL27, RAB5B, OPA1, NDUFV3, NDUFV2, NDUFS8, NDUFV1, NDUFS2, NDUFB10, NDUFB9, NDUFB5, NDUFA9, CPT1A, ATP5C1, ATP5B, CUL3, SIRT7, MY
    Protein Size: 727
    Molecular Weight
    77 kDa
    Gene ID
    4719
    NCBI Accession
    NM_005006, NP_004997
    UniProt
    P28331
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