Relaxin 1 antibody (Middle Region)
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- Target See all Relaxin 1 (RLN1) Antibodies
- Relaxin 1 (RLN1)
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Relaxin 1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- EIVPSFINKD TETIIIMLEF IANLPPELKA ALSERQPSLP ELQQYVPALK
- Predicted Reactivity
- Human: 100%, Pig: 92%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against RLN1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human RLN1
- Top Product
- Discover our top product RLN1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 185 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Relaxin 1 (RLN1)
- Alternative Name
- RLN1 (RLN1 Products)
- Synonyms
- H1 antibody, H1RLX antibody, RLXH1 antibody, bA12D24.3.1 antibody, bA12D24.3.2 antibody, Rln antibody, rlx antibody, RELAX antibody, RLX1 antibody, RNL1 antibody, RLN1 antibody, RLX antibody, relaxin 1 antibody, RLN1 antibody, Rln1 antibody
- Background
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Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds, however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet.
Alias Symbols: H1, RLXH1, bA12D24.3.1, bA12D24.3.2
Protein Interaction Partner: RXFP1,
Protein Size: 185 - Molecular Weight
- 21 kDa
- Gene ID
- 6013
- NCBI Accession
- NM_006911, NP_008842
- UniProt
- P04808
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