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ELP2 antibody (Middle Region)

ELP2 Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787102
  • Target See all ELP2 Antibodies
    ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))
    Binding Specificity
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 22
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)
    Host
    • 21
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ELP2 antibody is un-conjugated
    Application
    • 10
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    EESGVWLEQV RVGEVGGNTL GFYDCQFNED GSMIIAHAFH GALHLWKQNT
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Characteristics
    This is a rabbit polyclonal antibody against ELP2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ELP2
    Top Product
    Discover our top product ELP2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 826 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))
    Alternative Name
    ELP2 (ELP2 Products)
    Synonyms
    zgc:153559 antibody, SHINC-2 antibody, STATIP1 antibody, StIP antibody, AU023723 antibody, Epl2 antibody, StIP1 antibody, Statip1 antibody, F14J22.24 antibody, elongator protein 2 antibody, elongator acetyltransferase complex subunit 2 antibody, elongator protein 2 antibody, elp2 antibody, ELP2 antibody, Elp2 antibody
    Background
    ELP2 regulates the ligand-dependent activation of STAT3. ELP2 acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
    Alias Symbols: FLJ10879, SHINC-2, STATIP1, StIP
    Protein Interaction Partner: UBC, FAM96B, CIAO1, PAAF1, WRNIP1, ELP3, NRBP1, CD2AP, KIAA1033, USP34, SNRPB2, PRPSAP2, KIF5B, MMS19, IKBKAP, ELP4, CTDP1, STAT5B, STAT1, JAK2, JAK1, STAT3, TYK2,
    Protein Size: 826
    Molecular Weight
    92 kDa
    Gene ID
    55250
    NCBI Accession
    NM_018255, NP_060725
    UniProt
    Q6IA86
    Pathways
    Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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