ASXL2 antibody (Middle Region)

Catalog No. ABIN2787104

Product Details anti-ASXL2 Antibody

Target: ASXL2 (Additional Sex Combs Like 2 (ASXL2))

Binding Specificity: Middle Region

Reactivity: Human, Pig, Rabbit, Rat, Dog, Mouse, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASXL2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EEAPVSWEKR PRVTENRQHQ QPFQVSPQPF LNRGDRIQVR KVPPLKIPVS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ASXL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASXL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1435 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASXL2

Target: ASXL2 (Additional Sex Combs Like 2 (ASXL2))

Alternative Name: ASXL2 (ASXL2 Products)

Synonyms: asxh2 antibody, ASXH2 antibody, 4930556B16Rik antibody, mKIAA1685 antibody, additional sex combs like 2, transcriptional regulator antibody, additional sex combs like 2 (Drosophila) antibody, Asxl2 antibody, ASXL2 antibody, asxl2 antibody

Background: ASXL2 is a human homolog of the Drosophila asx gene. Drosophila asx is an enhancer of trithorax (see MIM 159555) and polycomb (see MIM 610231) (ETP) gene that encodes a chromatin protein with dual functions in transcriptional activation and silencing (Katoh and Katoh, 2003 [PubMed 12888926]).
Alias Symbols: ASXH2, DKFZp686C1968, FLJ10898, KIAA1685
Protein Interaction Partner: UBC, HECW2, PRPF40A, APP, BAP1, TRAF6,
Protein Size: 1435

Molecular Weight: 154 kDa

Gene ID: 55252

NCBI Accession: NM_018263, NP_060733

UniProt: Q76L83

Pathways: Positive Regulation of fat Cell Differentiation